My opinion regarding amplifier noise, supported by theory and some facts in RF wave propagation is this:
Much of the noise interference occurs in the frequency bands above the threshold of human hearing, generally considered to be 20kHz, but most people cannot hear average-level sound above 16kHz. However, there are lower or higher frequency harmonics generated outside the amplifier that may interfere with the input or amplified signal, such as a AM or HAM radio in the LF band (30kHz to 300kHz). If it is part of the input signal, it gets amplified along with everything else and can cause musical signals to sound "smeared" or otherwise unclear, unless a capacitor cuts off anything above the audible spectrum.
Of course the worst offender is any noise in the audible spectrum, such as 60Hz (heard at 120Hz) that is radiated into the amplifier can be heard in the background of the musical signal. This could be hum or ringing sounds, especially if the amplifier is not shielded and the source of the interference is external, such as a fluorescent light ballast, or a noisy switch mode power supply. If the amplifier power supply is not operating correctly, it can be the source of interference, too.
What we can do:
For external RF noise interference in the power lines, ensure the metal case around the amplifier is grounded. This will drain noise to ground on a low impedance path. Extreme cases might require a low pass filter to cut off the offending frequency, this is best done with a resistor-capacitor (RC) filter in the power supply such as: Mouser P/N 80-PMR210MB5220M100 $3.81ea. Possibly a power conditioner to plug the amplifier into, but it will have to be a large one, our WOPL amps can draw 2000Watts.
For AC (60Hz) hum on the power line (if you have noise on all components plugged into that circuit), try and find the source (often a defective or low quality appliance) with an AM radio tuned off-station and walk around the house. It it turns out to be everywhere, it could be a noisy power line transformer. Good news, the utility company will come out and replace it for free and usually very quickly.
Bypass other sources of AC noise (power strips, fluorescent light ballasts, switch mode power supplies (SMPS), etc.) with AC-rated (labeled X2) capacitors of sufficient voltage. I like these: Mouser P/N 539-104MACQRL150 $8.32ea.
Then, bypass sources inside the amplifier such as switches, bridge rectifiers, relays, etc. (WOA Backplane Boards also accomplish this).
I always do more than the minimum, who knows where the amplifier might end up, some guys garage next to an old battery charger, don't ask?