I have several of these, and I run them in any system with a cassette deck or R2R. My Pioneer RT-707s and RT-909 do not have Dolby NR, and the PL1000 cuts hiss out completely. It also does an AMAZING job on 8-tracks. It's redundant for the cassettes i record - quality Cr02 tape with Dolby NR. But it works amazingly on pre-recorded cassettes, with or without Dolby.
I've also used it to remove the hiss on the David Bowie Live Santa Monica 72 CD, when recording it to R2R. (No sense recording more hiss than a tape is already going to give me).
There are both Series I and Series II units. The Series II looks nicer and sounds better with no modifications. The stock Series I has troublesome buttons that are really difficult to deoxit, and the solder joints on the motherboard for the connectors to each daughter board are often cold and cracked. This is easily fixable though. The Series I has a little more gain, and can push things into distortion when the range expansion is used. I prefer using the Series I only as noise reduction, not as range expansion, for this reason. The Series II does not have this issue, it sounds clean and undistorted, and the range expansion actually helps with noise reduction as well. That said, there are upgrades to fix the Series I, and make it much, much better. Check it here:
http://home.onemain.com/~jvandyke/id9.html
I actually have a tech working on one of my series I noise reduction units now. (I have two Series I and two Series II units, three R2Rs and four tape decks)
Charles.